Traditionally, treatment for osteoarthritis has been limited to relieving pain. Scientists have found hope that drugs used to treat osteoporosis may be useful in treating not only osteoarthritis (OA) pain, but cartilage damage as well.
Osteoporosis is a condition in which bone tissue breaks down faster than it is replaced, causing the bones to become brittle and prone to fracture. Bisphosphonates, a class of drugs commonly prescribed for osteoporosis, work by inhibiting cells called osteoclasts that break down bone. Researchers believe they may work similarly for OA, by inhibiting the activity of osteoclasts in the bone beneath the cartilage in affected joints.
In animal studies, bisphophonates have shown to reduce OA progression – as measured by the severity of cartilage damage and bony overgrowth – by as much as 30–40%. Continue reading Potential New Treatment for Osteoarthritis
Widely used by doctors to soften forehead wrinkles and reduce uncontrollably sweaty armpits, researchers are exploring botulinum toxin as a potential therapy for osteoarthritis (OA) pain.
“The Botox story is very intriguing,” says David Felson, MD, MPH, professor of medicine and epidemiology at Boston University School of Medicine. “It isn’t just muscles. It can paralyze nerves. Just like celebrities injecting it into wrinkles, it could have the same effect on a hip muscle. Botox could paralyze the muscle that is transmitting pain.”
This toxin may eventually be used to treat OA patients whose pain is not sufficiently controlled by traditional medicines like NSAIDs or analgesics, and for patients who may experience adverse effects from those medicines, says Dr. Felson.
Continue reading Studies Suggest Botox May Ease Osteoarthritis Pain
Focusing on either aerobic conditioning or resistance training – especially moves that target the quadriceps muscles, which help support the knee – is the most effective exercise approach for reducing pain from knee osteoarthritis (OA), according to a 2014 study published in Arthritis & Rheumatism.
Experts have long known that exercise can help reduce pain and improve function for people with knee OA. But what type of exercise is best, and how much, are subject to debate. The new study, an analysis of 48 previously published trials, aimed to provide answers.
Continue reading What is the Best Exercise for Knee OA?