Two drugs used for decades to treat inflammatory forms of arthritis may also benefit some people with hand osteoarthritis (OA). That’s according to two new studies presented at the 2019 American College of Rheumatology (ACR) annual meeting in early November in Atlanta.
A new study found that hydroxychloroquine, a disease-modifying antirheumatic drug (DMARD) sometimes used to treat rheumatoid arthritis (RA) and lupus, does not reduce pain related to osteoarthritis (OA) of the hand, possibly ending the hope for an easy solution to a challenging problem.
Pain from hand OA affects an estimated 3 percent to 15 percent of adults over 60 and up to 31 percent of those over 70, making daily tasks difficult and diminishing quality of life. Increasing evidence suggests that low levels of inflammation may be an important source of pain in hand OA, at least in some people. Few medications are effective for hand OA other than traditional pain relievers, such as nonsteroidal anti-inflammatories (NSAIDs), acetaminophen and, in more intractable cases, opioids – all of which have side effects and can’t be used in certain populations. Researchers have been looking for other treatments.
About 40 percent of adults in the United States are likely to develop osteoarthritis (OA) in at least one hand by age 85, and some people are more at risk than others, according to researchers at the Centers for Disease Control and Prevention (CDC). Their findings were published recently in the journal Arthritis & Rheumatology.
Continue reading Hand OA Risk Higher for Women, Caucasians, Overweight People