Tag Archives: PTOA

The Arthritis Foundation Announces Funding Opportunities for OA Researchers & Fellowship Programs

The Arthritis Foundation announces funding opportunities for two of our scientific pillar programs. These programs use patient and peer review committees for their decision-making process. Researchers and fellowship directors interested in applying for these awards should view the full application on proposalCENTRAL.

Advancing Osteoarthritis (OA) Treatments:
Clinical Trial Network Request for Proposals (RFP)

The first opportunity for funding is extended to researchers through the OA virtual Center of Excellence (OA vCOE). The center oversees our Clinical Trial Network, bringing together researchers interested in finding new treatments and cures for osteoarthritis, which is the most prevalent form of the disease. The OA vCOE is seeking proposals for research projects aimed at post-traumatic OA (PTOA), the type of OA that is caused by bone or joint injuries.

Competitive proposals from independent researchers and research institutions will be considered that aim to better understand how to prevent and treat PTOA. The focus of this RFP is on clinical research that ultimately, whether directly or indirectly, impacts patient care and identifies ways to meaningfully improve health-related outcomes for patients with PTOA. The deadline for applications is November 1, 2019.

Cultivating A New Generation of Rheumatologists:
Request for Applications (RFA)
The second funding opportunity is extended to clinical rheumatology training institutions. Fellowship directors from qualified institutionswith programs that are establishing new post-residency fellowship positions in clinical rheumatology adult and/or pediatric programs — are eligible to apply. This award will provide a grant offering up to three years of initial support, for a maximum of $150,000. Grants will be awarded to programs that meet the established criteria. The deadline for applications is December 16, 2019.

If you have questions about these programs or wish to be added to our mailing list for future funding opportunities, please contact AFScience@arthritis.org.

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dr christian lattermann

Researchers on the Path to a Cure – Spotlight on Dr. Christian Lattermann

Osteoarthritis Center of Excellence Research Story

Over the last month, we’ve kept you updated on the work being done by the researchers in our osteoarthritis (OA) center of excellence (OA COE). The COE is currently funding three Clinical Trial Network demonstration studies that may lead to better diagnosis and earlier treatments for arthritis. Researchers from six different institutions will collaborate in various aspects of these cutting-edge studies. This is the last in a series of three blogs describing these studies.

Most people with partial or complete rupture of the anterior cruciate ligament (ACL) develop post traumatic OA (PTOA) within 10 to 20 years after their injury. Unfortunately, current ACL injury treatment options (both surgical and non-surgical) are successful in the short-term but do little or nothing to reduce the risk of developing PTOA later.

All three of the current OA COE are demonstration projects that build on knowledge gained from earlier foundation-funded ACL and PTOA research.

Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Christian Lattermann

delivering on discovery

Researchers on the Path to a Cure – Spotlight on Dr. Hongsik Cho

Big things come in small packages, and Dr. Hongsik Cho is very familiar with this phenomenon. When we first introduced Dr. Cho in August 2016, he was beginning work on his 2-year Arthritis Foundation-funded project, “A Novel Method of Detecting and Treating Early PTOA Using Smart Nanosome”.  He and his team are studying two things: a new drug and a new drug delivery system.  The drug, called TPCA-1, works to prevent inflammation caused by post-traumatic osteoarthritis (PTOA).  The drug delivery system uses small packets called nanosomes that contain TPCA-1 and a fluorescent dye that illuminates the nanosomes’ path once injected into mice.

Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Hongsik Cho