Keep up-to-date on the latest rheumatoid arthritis (RA) research with our brief research summaries.
Smoking, Obesity Make RA Harder to Control
Remission in RA patients can be harder to achieve in those who are overweight or smoke, according to a recent study. American and Canadian researchers who collected data on more than 1,100 patients receiving standard treatment for RA found that sex (being female), excess weight and smoking were not significantly associated with symptom severity early on. However, all three factors influenced how much symptoms improved over time. The most dramatic differences in symptoms were seen in patients who were overweight or obese and smoked, the study found.
Source: ACR/ARHP Annual Meeting, November 2016
Continue reading RA Research Briefs: Remission, Biologics, Exercise
People with rheumatoid arthritis (RA) who are obese are less likely to achieve disease remission than their non-obese counterparts, according to a meta-analysis published in May in Arthritis Care and Research. The review also found that obesity was associated with higher levels of disease activity and pain, suggesting excess weight may negatively affect overall outcomes in RA. This meta-analysis supports earlier research, including a study presented at the 2015 annual meeting of the American College of Rheumatology.
Continue reading New Research: Obesity May Reduce the Chance of RA Remission by as Much as Half
If you have a few – or a lot – of pounds to lose, you know that carrying excess weight around can stress your painful or fragile joints. But research shows that the mechanical effects of weight are just part of the problem.
Fat itself releases chemicals including tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1) that promote inflammation. These chemicals may not only increase the risk of developing some forms of arthritis, but they may also increase arthritis severity or make it harder to control.
In fact a study presented at the 2015 annual meeting of the American College of Rheumatology found that for people with early rheumatoid arthritis (RA), being overweight or obese can reduce the chance of achieving sustained remission.
Continue reading Being Overweight Can Hurt Rheumatoid Arthritis Remission