Tag Archives: arthritis biologics

Biologics Rheumatoid Arthritis Cancer

Biologics Appear Safe for Some Rheumatoid Arthritis Patients Who’ve Had Cancer

Researchers set out to answer a pressing question: Is it safe for rheumatoid arthritis (RA) patients who have had cancer in the past to use a biologic drug rather than a traditional disease-modifying antirheumatic drug (DMARD), like methotrexate, to control their disease? Their answer, detailed in a study recently published online in the journal Rheumatology, is reassuring. They found that patients with a previous malignancy who later took certain biologics did not appear to have an increased risk of cancer after an average of five years, compared to those who took a traditional DMARD.
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Jakinibs Rheumatoid Arthritis Treatment

Will Jakinibs Change Your Rheumatoid Arthritis Treatment?

An emerging class of medications called janus kinase inhibitors (JAK inhibitors, or jakinibs) is offering new hope to patients with rheumatoid arthritis (RA) who don’t find relief with other treatments.

What are Jakinibs?

Jakinibs are a new class of medication, sometimes called oral biologics. The word “biologic” is misleading, however, because jakinibs work in an entirely different way than the biologics that have been used to date. Jakinibs are small molecules that work inside cells. Traditional biologics such as etanercept (Enbrel), adalimumab (Humira), abatacept (Orencia) and Infliximab (Remicade) block pro-inflammatory cytokines from outside.

Jakinibs are taken by mouth. Traditional biologics are given through infusions or injections.

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