psoriatic psa treatment guideline

PsA Research Briefs: Comorbidities

Keep up-to-date on the latest psoriatic arthritis (PsA) research with our brief research summaries.

PsA May Put Liver at Risk

People with PsA may have an increased risk of liver disease, according to a new study that followed more than a million people for an average of 6 years. People with psoriasis were 37% more likely to develop liver disease than those without inflammatory diseases, the study found. Those with PsA were 38% more likely to have liver disorders. Taking methotrexate further increased their risk.

SOURCE: Journal of Investigative Dermatology, April 2018

Cardiovascular Risk Factors Undertreated

A large percentage of patients with psoriasis and psoriatic arthritis have modifiable risk factors for cardiovascular disease, but many are not being adequately treated for them, a new study shows. In the study of 2,254 patients from centers in Canada, the United States, and Israel, 87.6% had at least one modifiable cardiovascular risk factor (including high blood pressure, high cholesterol, diabetes, obesity or smoking). The study found 59.2% with hypertension and 65.6% with high cholesterol were undertreated. Because psoriatic disease itself is a risk factor for cardiovascular disease, the authors say strategies to improve cardiovascular risk factors among people with psoriasis and psoriatic arthritis is important.

SOURCE: Journal of Rheumatology, February 2018

Psoriasis Severity Linked to Diabetes Risk

Scientists have recognized for some time a link between psoriasis and diabetes risk. A new study shows that more widespread psoriasis means greater risk. The British study, which analyzed data on 8,124 adults with psoriasis and 76,599 adults without, found that those with psoriasis covering two percent of their body surface area (BSA) had a 21% greater risk of type-2 diabetes than those without psoriasis. For those with 10% BSA coverage, the risk of diabetes was 64% higher than for people without psoriasis, and for those who had psoriasis over 30% of their BSA, the risk of diabetes was doubled.

SOURCE: Journal of the American Academy of Dermatology, February 2018

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