Disease-modifying antirheumatic drugs (DMARDs) are not effective treatments for hand or knee osteoarthritis (OA), according to a new meta-analysis. The drugs are commonly used to treat rheumatoid arthritis (RA) and other forms of inflammatory arthritis, but researchers in the United Kingdom (UK) found they were no better than placebo for OA pain. Their findings appeared in June 2018 in Rheumatology.
DMARDs aren’t pain medications. They’re meant to slow the disease and prevent further damage to joints and organs by suppressing inflammation. When DMARDs work, pain usually improves as inflammation gets under control.
Continue reading Disease-Modifying Drugs No Help for OA Pain
A new study takes a look at which approaches are best to bring relief to people with knee osteoarthritis (OA), a condition that affects approximately 20 percent of people over the age of 45 in the United States.
Knee OA can be extremely painful and limit a person’s ability to function. Although there is no cure, numerous treatments are available to reduce symptoms, including over-the-counter and prescription drugs. Exercising and losing weight if a patient is overweight or obese also can help. Total knee replacement surgery is effective but is done only in cases where the disease is advanced and it’s medically necessary.
So, which treatment is best? To help sort out the choices, a group of researchers set out to assess how the available non-surgical drug treatments stack up against each other for providing pain relief and improving physical function. The authors did not address lifestyle changes, like weight loss and exercise. The study was published recently in Journal of American Academy of Orthopaedic Surgeons (JAAOS).
Continue reading Study Ranks Treatments for Knee OA
Chondroitin sulfate improves osteoarthritis (OA) knee pain and functional limitations in walking and daily activities as effectively as the anti-inflammatory drug celecoxib (Celebrex), according to a new study published recently in Annals of the Rheumatic Diseases. But U.S. readers should know, there’s a catch: the researchers tested a version of chondroitin sulfate that is not available in this country.
Continue reading A New Study Finds Pharmaceutical Chondroitin Helps Knee OA Pain and Function