Dr. Sanja Arandjelovic has been studying inflammation and arthritis for a while – specifically, how a gene called ELMO1 is related to arthritis symptoms in mice. In 2010, the Arthritis Foundation awarded Dr. Arandjelovic the Philip S. Maaram Esq. Research (Planned Giving) 3-year grant for a project that studied cell enzymes related to joint inflammation in rheumatoid arthritis (RA) in mice.
During this study, Dr. Arandjelovic worked with Dr. Kodi Ravichandran and his research team at the University of Virginia on a related project, examining the process of joint inflammation in RA. Their work may provide clues to why the pain flare-ups associated with RA occur – and lead to new treatments.
Continue reading ELMO1 – More Than Just Your Friendly, Red Sesame Street Character!
Meet Shannan O’hara-Levi
When Shannan O’hara-Levi was only 7 months old, her mother noticed that she would wake up from naps crying and grabbing at her knees. Mrs. O’hara took her to the doctor, only to be brushed off and told it was just “growing pains” that would eventually go away. Ironically, a few years later at a routine checkup, the pediatrician asked Mrs. O’hara why Shannan wasn’t brought in earlier for her red, swollen knees. That’s when Shannan was finally diagnosed with juvenile arthritis (JA). Continue reading No One Should Be in Debilitating Pain, Especially at 3 Years Old
Why is my immune system attacking my joints? What is the cause? If you have rheumatoid arthritis (RA), this is something you have probably wondered at some point. It’s something Dr. Edward Doherty has wondered as well, and is currently studying. Dr. Doherty and his co-investigator, Dr. Pathricia Tilstam are studying key cells that drive inflammation in their 2-year Arthritis Foundation-funded project, “MIF/CD74 signaling as a new candidate for immunotherapy of rheumatoid arthritis”. With autoimmune disorders like RA, something triggers the immune system to malfunction and attack healthy cells, causing inflammation and disease. Dr. Doherty and Dr. Tilstam are looking for some of the triggers to help develop more effective treatments to stop progression and joint destruction.
Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Edward Doherty
Last week at the Conference of Champions, Andrea Avery, author and Arizona-based Foundation volunteer, shared her gripping story, intertwining her love for piano and the reality of her arthritis. Beyond sharing her personal story with hundreds of volunteers in Phoenix, she also met and performed with her inspiration, Byron Janis, master and renowned pianist. See below for an excerpt from her book, Sonata: A Memoir of Pain and the Piano.
Continue reading Andrea Avery: Composing My Life
Champion of Yes has come to mean different things to different people. To many, it means refusing to let arthritis win – to stand up, push back and say, “Enough is enough. I won’t let arthritis stop me or anyone else from living life to its fullest!”
Continue reading Winterhoff Arthritis Scholarship Goes National – Eight 2017 Recipients Announced