Lupus, a chronic, systemic, autoimmune disease, can affect many parts of the body. It affects people of all races and far more women are affected than men. Lupus nephritis (kidney disease) is seen to some degree in about 60% of lupus patients and can lead to kidney failure and the need for dialysis if not treated appropriately. Continue reading Decision Aid for Women With Lupus Nephritis
Lupus is a chronic, autoimmune disease and affects a wide part of the body, including the joints, kidneys, skin, blood, brain and other organs. One of our six Delivering on Discovery projects focuses on Lupus and lung disease. “Lupus is a complex disease. It affects many organs. The number of lupus patients with lung inflammation is probably underestimated. Yet it negatively impacts the quality of life in these patients,” explained Dr. Caroline Jefferies. “And while we have a basic understanding about how lupus affects various organs, we need to better understand how it affects the lungs to better manage and treat it.”
Dr. Jefferies is focusing on the lungs with her 3-year Arthritis Foundation-funded project, “Inflammatory neutrophils in lupus lung disease – novel cellular target”.
Ninety percent of people in the United States who have the chronic autoimmune disease lupus are women and, according to two new studies published recently in Arthritis & Rheumatology, large proportions are Hispanic or Asian. Like African-Americans, these two ethnic/racial groups are not only at higher risk of lupus than whites, they’re also more likely to have aggressive forms of the disease, researchers in New York and San Francisco found.
Lupus, or systemic lupus erythematosus (SLE), an affect virtually every organ system, and symptoms vary widely. Some patients have relatively mild skin and joint symptoms that may go into remission for long periods. Others have cognitive (neuropsychiatric) manifestations or life-threatening complications such as lung, heart and kidney problems.