Tag Archives: arthritis cure

delivering on discovery

Researchers on the Path to a Cure – Spotlight on Dr. Hongsik Cho

Big things come in small packages, and Dr. Hongsik Cho is very familiar with this phenomenon. When we first introduced Dr. Cho in August 2016, he was beginning work on his 2-year Arthritis Foundation-funded project, “A Novel Method of Detecting and Treating Early PTOA Using Smart Nanosome”.  He and his team are studying two things: a new drug and a new drug delivery system.  The drug, called TPCA-1, works to prevent inflammation caused by post-traumatic osteoarthritis (PTOA).  The drug delivery system uses small packets called nanosomes that contain TPCA-1 and a fluorescent dye that illuminates the nanosomes’ path once injected into mice.

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Researchers on the Path to a Cure – Spotlight on Dr. James Jarvis

“Why did my child get arthritis?” This parent-driven question is at the heart of Dr. Jim Jarvis’s juvenile idiopathic arthritis (JIA) Arthritis Foundation-funded project, “Interplay between genetics and epigenetics in polyarticular JIA”.

“This is less about an illness driven by inherited genes and more about how the environment affects gene expression,” explained Dr. Jarvis. “It’s been shown that only about 30 percent of the risk for developing JIA can be attributed to gene variations.”

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Researchers on the Path to a Cure – Spotlight on Dr. Christine Beeton

Venom can kill, but this research proves it could help do the opposite. More specifically, some chemicals found in venom could act as a treatment for disease. These chemicals come from a deadly reptile, but with the help of Dr. Christine Beeton, venom might be able to better the lives of multitudes of people.

Dr. Beeton and her research team are looking at the chemicals found in scorpion venom as a source of potential treatment for autoimmune diseases like rheumatoid arthritis (RA).

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Researchers on the Path to a Cure – Spotlight on Dr. C. Michael Stein

Every day, scientists work toward the advancement of rheumatoid arthritis (RA)treatment. And Dr. C. Michael Stein has made an exciting new discovery that could help these advancements along and predict how specific treatments will work.

Dr. Stein is looking at small molecules that have the potential to cause big problems.  His 5-year Arthritis Foundation-funded project, “Extracellular small RNAs in rheumatoid arthritis,” is looking at how small molecules of ribonucleic acid (RNA) in the blood may be markers for different diseases.

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Researchers on the Path to a Cure – Spotlight on Salah Ahmed

If you suffer from rheumatoid arthritis (RA), Dr. Salah Ahmed’s research project may be just your cup of (green) tea! Dr. Ahmed’s 2014 Innovative Research Grant project, “Mechanism of Mcl-1 regulation in RA by EGCG”, looked at the effects of an anti-inflammatory molecule found in green tea (epigallocatechin-3-gallate or EGCG) on a protein (Mcl-1) found in RA joints.

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Arthritis Foundation Registry Workshop Ushers in a New Scientific Strategy

For people with arthritis, they’ve only wanted one thing since their diagnosis: a cure. At the Arthritis Foundation, we want the same thing.

With that in mind, last week we convened the who’s who of registry experts from around the world for the Arthritis Foundation Registry Workshop: Improving Health Outcomes for People with Arthritis. The goal of the workshop was to find common ground for how registries can work together to improve health outcomes for people with arthritis and related diseases. This important work is helping more people become a Champion of Yes.

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