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Psoriatic Arthritis Research Briefs: Fractures, Depression, RCI

Keep up-to-date on the latest psoriatic arthritis (PsA) research with our brief research summaries.

Fracture Risk Factors Increased in PsA
If you have PsA, it’s important to pay attention to your bones as well as your skin and joints, according to a recent study. The study found increased risk factors for osteoporotic fractures among more than 168,100 people with either PsA or psoriasis compared to people with rheumatoid arthritis and controls. Risk factors included diabetes, smoking, alcohol and oral corticosteroid and antidepressant use. The authors say screening and management of osteoporosis should be considered for patients with psoriasis and PsA.

Source: Annals of the Rheumatic Diseases, May 2017

Depression Linked to Increased PsA Risk
People with psoriasis who also are depressed may be at increased risk for developing PsA, new research shows. Using a primary care database of 73,447 patients followed for 25 years, Canadian researchers found that people with psoriasis who were also diagnosed with a major depressive disorder were up to 37% more likely to develop PsA.

The authors say their study is among the first to offer insight into how depression may be linked to psoriatic arthritis and suggests a need for heightened prevention and management of major depressive disorders in patients with psoriasis.

Source: Journal of Investigative Dermatology, April 2017

 

RCI May Help Hard-to-Control  PsA
When multiple treatments fail to control PsA, a recent study suggests repository corticotrophin injection (RCI) may be a safe and effective treatment option. In a small study of patients with refractory PsA, all nine patients experienced at least transient improvement in skin and joint disease with RCI; however, three had to stop the drug due to side effects.

Source: Open Access Rheumatology, published online November 2016

 

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