Dr. Sanja Arandjelovic has been studying inflammation and arthritis for a while – specifically, how a gene called ELMO1 is related to arthritis symptoms in mice. In 2010, the Arthritis Foundation awarded Dr. Arandjelovic the Philip S. Maaram Esq. Research (Planned Giving) 3-year grant for a project that studied cell enzymes related to joint inflammation in rheumatoid arthritis (RA) in mice.
During this study, Dr. Arandjelovic worked with Dr. Kodi Ravichandran and his research team at the University of Virginia on a related project, examining the process of joint inflammation in RA. Their work may provide clues to why the pain flare-ups associated with RA occur – and lead to new treatments.
Continue reading ELMO1 – More Than Just Your Friendly, Red Sesame Street Character!
More than 15,000 doctors, nurses, physical therapists, researchers, scientists and others with interest and/or expertise in rheumatology gathered in Chicago in late October for the American College of Rheumatology’s Annual Meeting. The Arthritis Foundation had a contingent of “patient representatives” attending to provide the perspective and voice of people living with arthritis. They fanned out to attend sessions, view and present posters and collect information about exciting new developments in the field. Here are their notes from the final sessions of the meeting.
“Patient perspective,” “patient-reported outcomes” and “shared decision making” are hot topics at the American College of Rheumatology (ACR) 2018 Annual Meeting in Chicago. In fact, many patients – including some of the Arthritis Foundation’s patient representatives – are attending the four-day event, which highlights rheumatology developments and draws medical professionals and researchers from around the world.
Donna Dernier, one of the Arthritis Foundation’s Patient Reps, reports that she ran into Hazel Breland, PhD, the incoming president of the Association of Rheumatology Health Professionals (AHRP), a division of the ACR. “She noticed my Patient Rep Sticker and stopped to say how glad she was to see patients involved with so many aspects of health care,” says Dernier.
Besides attending the conference, patients are getting involved in many ways. Four patients affiliated with the Arthritis Foundation exhibited posters during the Patient Perspectives Poster session on Sunday.
Continue reading Patient Perspectives at the American College of Rheumatology Conference
Living Your Yes with RA is a personalized goal-setting event brought to you by the Arthritis Foundation. This free forum gives you the opportunity to learn ways that can help you say Yes more than No, despite the challenges of living with rheumatoid arthritis (RA). You’ll get expert advice from a local rheumatologist plus guidance on setting goals that can help you live life to the fullest. Let us help you manage your RA, as well as communicate effectively with your own doctor.
Continue reading 2018 Living Your Yes With RA
Why is my immune system attacking my joints? What is the cause? If you have rheumatoid arthritis (RA), this is something you have probably wondered at some point. It’s something Dr. Edward Doherty has wondered as well, and is currently studying. Dr. Doherty and his co-investigator, Dr. Pathricia Tilstam are studying key cells that drive inflammation in their 2-year Arthritis Foundation-funded project, “MIF/CD74 signaling as a new candidate for immunotherapy of rheumatoid arthritis”. With autoimmune disorders like RA, something triggers the immune system to malfunction and attack healthy cells, causing inflammation and disease. Dr. Doherty and Dr. Tilstam are looking for some of the triggers to help develop more effective treatments to stop progression and joint destruction.
Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Edward Doherty
It’s no secret that obesity is associated with a higher risk of developing rheumatic diseases and worse outcomes. Three new studies, presented recently at the 2017 Annual Meeting of the American College of Rheumatology, characterize in greater detail the harmful effects of excess weight in people who have rheumatoid arthritis (RA) or axial spondyloarthropathy (axSpA).
Continue reading Three New Studies Show How Extra Weight Worsens Inflammatory Arthritis
Last week at the Conference of Champions, Andrea Avery, author and Arizona-based Foundation volunteer, shared her gripping story, intertwining her love for piano and the reality of her arthritis. Beyond sharing her personal story with hundreds of volunteers in Phoenix, she also met and performed with her inspiration, Byron Janis, master and renowned pianist. See below for an excerpt from her book, Sonata: A Memoir of Pain and the Piano.
Continue reading Andrea Avery: Composing My Life
Venom can kill, but this research proves it could help do the opposite. More specifically, some chemicals found in venom could act as a treatment for disease. These chemicals come from a deadly reptile, but with the help of Dr. Christine Beeton, venom might be able to better the lives of multitudes of people.
Dr. Beeton and her research team are looking at the chemicals found in scorpion venom as a source of potential treatment for autoimmune diseases like rheumatoid arthritis (RA).
Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Christine Beeton
Every day, scientists work toward the advancement of rheumatoid arthritis (RA)treatment. And Dr. C. Michael Stein has made an exciting new discovery that could help these advancements along and predict how specific treatments will work.
Dr. Stein is looking at small molecules that have the potential to cause big problems. His 5-year Arthritis Foundation-funded project, “Extracellular small RNAs in rheumatoid arthritis,” is looking at how small molecules of ribonucleic acid (RNA) in the blood may be markers for different diseases.
Continue reading Researchers on the Path to a Cure – Spotlight on Dr. C. Michael Stein
Earlier this year, we awarded funding to six scientists for projects submitted that show remarkable innovations and steps towards finding a cure for arthritis and related diseases. For the first time, we included patient input in selecting the projects that showed the most promise and meant the most to them.
Continue reading Arthritis Patients Help to Select Scientific Projects That Show Promise Towards Finding a Cure for Arthritis