Category Archives: Research

Arthritis Research Dr Lefebvre

Researchers on the Path to a Cure – Spotlight on Dr. Veronique Lefebvre

What do skin and cartilage have in common? It depends on who you ask. Dr. Veronique Lefebvre, a researcher at Cleveland Clinic Lerner Research Institute, is currently working on a 2016 foundation-funded project called “Quality-by-Design approach to create articular cartilage from pluripotency” that connects the dots between skin and cartilage. Dr. Lefebvre and her team are developing a protocol that starts with skin cells and ends with knee cartilage.
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Dr. Jose Scher RA Research

Researchers on the Path to a Cure – Spotlight on Dr. Jose Scher

Dr. Jose U. Scher, a current Arthritis Foundation-funded investigator, has been looking at the relationship between bacteria and inflammatory diseases for more than 10 years. Dr. Scher’s current Arthritis Foundation funded project, “Pan-Microbiome in At-Risk Subjects and New-Onset Rheumatoid Arthritis (RA),” looks at the relationship of bacteria (or “microbiome” in the mouth, lungs, and intestines) and the development of RA.
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2017 Osteoarthritis Patient-Focused Drug Development Meeting

Highlights from 2017 Osteoarthritis Patient-Focused Drug Development Meeting

Close to 200 patients, FDA staff, industry leaders, members of the media and academic personnel listened or participated in the groundbreaking Osteoarthritis Patient-Focused Drug Development meeting on March 8. The meeting was a forum for OA patients to share their experiences with the disease and talk about the signs and symptoms that matter most to them.
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Arthritis Research Dr. Virginia Kraus

Researchers on the Path to a Cure – Spotlight on Dr. Virginia Kraus

Research on bacteria that live within our bodies has progressed in recent years and is gaining respect in the scientific community. Most of these bacteria live in our gut, and scientists think they shape our health in a number of ways – some good and some bad. Dr. Virginia Kraus is currently researching bacteria in her 2-year Arthritis Foundation-funded project, “The Role of Low-Grade Endotoxemia in Osteoarthritis.” Her project looks at one molecule made by harmful bacteria.
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Dr. Delesha Carpenter arthritis research

Researchers on the Path to a Cure – Spotlight on Dr. Delesha Carpenter

Many of us go to multiple doctors’ appointments throughout the year. Between those appointments, work, family life and other things it can be hard to process and remember the information your doctor tells you. One of our funded researchers, Dr. Delesha Carpenter is looking at how well Rheumatoid Arthritis (RA) patients recall information about newly prescribed DMARDs – disease-modifying antirheumatic drugs. Her 3-year Arthritis Foundation funded research project, called “Understanding how RA patients process conflicting information about DMARDs”, was recently presented at the 2016 ACR Annual Meeting & Conference in November.
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Osteoarthritis Drug Development Meeting

Arthritis Foundation to Host Meeting for Osteoarthritis Patients to Share their Stories with the FDA

Last year, the Arthritis Foundation cosponsored the Accelerating Osteoarthritis (OA) Clinical Trials Workshop with the US Food and Drug Administration (FDA). The focus of the workshop aimed at identifying ways to get new diagnostics & treatments to clinics faster for the arthritis community. Important key takeaways from the workshop included a focus on patients – how they need to be more involved in the scientific discovery process and that scientists should consider their needs and wants in designing clinical trials.
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Dr. Farshid Guilak

Researchers on the Path to a Cure – Spotlight on Dr. Farshid Guilak

In July, we reported on Dr. Farshid Guilak’s remarkable breakthrough in orthopedic and osteoarthritis research. That research found a way to grow new cartilage on a hip joint shaped scaffold, using stem cells. His current Arthritis Foundation-funded project, “Engineering New Biologic Therapies for Arthritis,” is just as trailblazing.
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Ankylosing Spondylitis Side Effects Risk Factors

Women and Long-Standing Ankylosing Spondylitis Patients at Risk for Other Conditions

Women who have ankylosing spondylitis and men and women who have had the disease longer have an increased risk of developing potentially debilitating symptoms beyond the joints, according to a new study presented at the American College of Rheumatology’s Annual Meeting.
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Dr. Wimmer Arthritis Foundation research

Researchers on the Path to a Cure – Spotlight on Dr. Markus Wimmer

The third part of our researcher spotlight series is with Dr. Markus Wimmer, Associate Chairman of the Department of Orthopedics and Director of Human Motion Analysis and Tribology at Rush University Medical Center in Chicago, IL. Dr. Wimmer is one of 11 researchers to receive funding in early 2016 for his innovative research project, which uses mobile technology to show how a non-invasive treatment can improve health outcomes for people with osteoarthritis (OA). Dr. Wimmer’s 2 year research project is called “Augmented Feedback Using Pressure Detecting Insoles to Reduce Knee Loading”. The purpose of his research is to look at the use of a pressure based insole to train the OA patient to walk in a way that will reduce pressure in the knees. Reducing knee joint pressure loads may help reduce pain and disease progression.
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heart attack stroke risk celebrex nsaids

Celecoxib: Not So Hard on the Heart?

The recent findings of a huge study may erase some concerns about a pain reliever that has long been saddled with a worrisome reputation: celecoxib (Celebrex). While all nonsteroidal anti-inflammatory drugs (NSAIDs) carry a warning that users have an increased risk for heart attacks and strokes, celecoxib is closely linked to two similar drugs that were taken off the market due to concerns about their cardiovascular safety. However, the new research suggests that celecoxib may not be more dangerous than other NSAIDs, and might even be safer in some important ways. Continue reading Celecoxib: Not So Hard on the Heart?