Category Archives: Juvenile Arthritis

CARRA study enrollment complete

New Large-scale Study to Make Personalized Medicine a Reality for Kids With JIA

Personalized treatments for children with arthritis will soon be a reality, thanks to a new research study supported by the Arthritis Foundation.

The study, the largest of its kind, is being done by the Childhood Arthritis and Rheumatology Research Alliance (CARRA), a North American research network that conducts collaborative research to find treatments and a cure for pediatric rheumatic diseases. The Arthritis Foundation has worked closely with CARRA since it was formed in 2002. Together, we’ve aligned our scientific agendas, and the Foundation has committed millions of dollars toward expanding juvenile arthritis research through CARRA.

Continue reading New Large-scale Study to Make Personalized Medicine a Reality for Kids With JIA

Giving Tuesday Shannan Ohara

No One Should Be in Debilitating Pain, Especially at 3 Years Old

Meet Shannan O’hara-Levi

When Shannan O’hara-Levi was only 7 months old, her mother noticed that she would wake up from naps crying and grabbing at her knees. Mrs. O’hara took her to the doctor, only to be brushed off and told it was just “growing pains” that would eventually go away. Ironically, a few years later at a routine checkup, the pediatrician asked Mrs. O’hara why Shannan wasn’t brought in earlier for her red, swollen knees. That’s when Shannan was finally diagnosed with juvenile arthritis (JA). Continue reading No One Should Be in Debilitating Pain, Especially at 3 Years Old

juvenile idiopathic arthritis pfdd announcement

PARTNERS Pediatric Learning Health System: New JIA Project Focuses on Improving Outcomes for Children

The Patients, Advocates, and Rheumatology Teams Network for Research and Service (PARTNERS) consortium was selected to receive a 2-year grant to implement a Pediatric rheumatology Learning Health System (LHS) that will work with networks in the Patient-Centered Outcomes Research Institute (PCORI) PCORnet Learning Healthcare System Collaborative.

The PARTNERS Pediatric LHS will provide support for patients with juvenile idiopathic arthritis (JIA) and their families to actively engage in care and self-management activities. JIA is a rare disease, making it difficult to study. Currently there is no cure for JIA. Recent advances in drug development have resulted in many therapies, including biologics. However, there remain many unanswered questions about how to use available therapies. While early diagnosis and initiation of treatment have proven to improve outcomes, variation exists in treatment patterns across providers, medical centers, and geographic locations.

Continue reading PARTNERS Pediatric Learning Health System: New JIA Project Focuses on Improving Outcomes for Children

carra grants 2018

Spring 2018 Childhood Research Grants Announced

We recently gave approximately $160,000 toward childhood arthritis research in the form of research grants. The grants are funded through the Childhood Arthritis and Rheumatology Research Alliance (CARRA); small grants were given to pediatric rheumatologists and fellows small grant research awards were given to third year fellowship students.

Continue reading Spring 2018 Childhood Research Grants Announced

dr jarvis - path to a cure

Researchers on the Path to a Cure – Spotlight on Dr. James Jarvis

“Why did my child get arthritis?” This parent-driven question is at the heart of Dr. Jim Jarvis’s juvenile idiopathic arthritis (JIA) Arthritis Foundation-funded project, “Interplay between genetics and epigenetics in polyarticular JIA”.

“This is less about an illness driven by inherited genes and more about how the environment affects gene expression,” explained Dr. Jarvis. “It’s been shown that only about 30 percent of the risk for developing JIA can be attributed to gene variations.”

Continue reading Researchers on the Path to a Cure – Spotlight on Dr. James Jarvis

Winterhoff Scholarship Awardees

Winterhoff Arthritis Scholarship Goes National – Eight 2017 Recipients Announced

Champion of Yes has come to mean different things to different people. To many, it means refusing to let arthritis win – to stand up, push back and say, “Enough is enough. I won’t let arthritis stop me or anyone else from living life to its fullest!”

Continue reading Winterhoff Arthritis Scholarship Goes National – Eight 2017 Recipients Announced

Dr. Rae Yeung Arthritis Research

Researchers on the Path to a Cure – Spotlight on Dr. Rae Yeung

Dr. Rae Yeung believes in collaboration and building networks to solve problems. Her current 3-year Arthritis Foundation-funded project, “Precision Decisions to STOP JIA”, is an example of that. The goal is to develop a tool that will predict treatment response to specific drugs. Dr. Yeung’s study focuses on a group of high-risk children with polyarthritis, one of the most severe forms of childhood arthritis that affects many joints and is difficult to treat.
Continue reading Researchers on the Path to a Cure – Spotlight on Dr. Rae Yeung

heart attack stroke risk celebrex nsaids

Celecoxib: Not So Hard on the Heart?

The recent findings of a huge study may erase some concerns about a pain reliever that has long been saddled with a worrisome reputation: celecoxib (Celebrex). While all nonsteroidal anti-inflammatory drugs (NSAIDs) carry a warning that users have an increased risk for heart attacks and strokes, celecoxib is closely linked to two similar drugs that were taken off the market due to concerns about their cardiovascular safety. However, the new research suggests that celecoxib may not be more dangerous than other NSAIDs, and might even be safer in some important ways. Continue reading Celecoxib: Not So Hard on the Heart?

Biosimilar For Arthritis Approved

FDA Approves Second Arthritis Biosimilar – Biosimilar Version of Drug Enbrel

The Food and Drug Administration (FDA) has approved etanercept-szzs (brand name: Erelzi), a biosimilar form of etanercept (Enbrel), to treat rheumatoid arthritis (RA), psoriatic arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis as well as plaque psoriasis. Earlier this year, infliximab-dyyb (Inflectra), a biosimilar version of infliximab (Remicade), became the first FDA-approved biosimilar for inflammatory types of arthritis in the U.S.
Continue reading FDA Approves Second Arthritis Biosimilar – Biosimilar Version of Drug Enbrel

CBS Sunday Morning Arthritis Foundation

CBS’s Sunday Morning Features 11-year-old Arthritis Foundation Advocate, Graci Diggs

Graci is 11-years-old and stands just five feet tall. But don’t let her age and size fool you. She’s wiser than most and has the stature of a superstar.

Graci has battled juvenile polyarticular arthritis for most of her life. As a member of our Advocate program, she has been very active fighting on behalf of people with arthritis.
Continue reading CBS’s Sunday Morning Features 11-year-old Arthritis Foundation Advocate, Graci Diggs