Americans of Asian and African descent have much higher risk than white and Hispanic Americans of developing rare but severe, sometimes life-threatening skin reactions to the gout drug allopurinol (Zyloprim), according to a new study published recently in Seminars in Arthritis & Rheumatism.
These two skin reactions, called Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), cause flu-like symptoms, a widespread rash, and large portions of the upper layer of skin (including mucus membranes) to blister and detach. They can also damage other major organs. SJS and TENS, which are believed to be different manifestations of the same disorder, are usually caused by a reaction to a drug (including acetaminophen [Tylenol] and certain antibiotics).
Continue reading Severe Skin Reactions to Gout Drug Allopurinol Linked to Race
As a former football player and wrestler who’d had three knee operations, Scott thought he knew pain. Then he had his first gout attack.
While the pain was new to him, Scott was familiar with gout because his dad had been living with it for 20 years. Gout, a form of inflammatory arthritis, develops in some people who have high levels of uric acid in the blood. The acid can form needle-like crystals in a joint and cause sudden, severe episodes of pain, , (tenderness and redness are not severe – focus on pain, warmth and swelling), warmth and swelling in the joints. For many people, including Scott, the first symptom of gout is excruciating pain and swelling in the big toe. Gout may also appear in another lower-body joint, such as the ankle or knee.
“Basically I described what happened, the doctor looked at my foot, told me I had gout and prescribed some pain medicine,” Scott says. “The pain medicine didn’t do much though. I stopped taking it after a few days and tried to manage around the pain.”
Continue reading Former Football Player Tackles Gout
National Gout Awareness Day is recognized annually on May 22 to help raise awareness around gout, a painful disease that affects approximately 8.3 million Americans.
Gout is a form of inflammatory arthritis that develops as a result of excess levels of uric acid in the blood, which results in a condition called hyperuricemia.. The uric acid can form needle-like crystals in a joint and cause sudden, severe episodes of pain, tenderness, redness, warmth and swelling.
Although gout appears to manifest itself suddenly as an acutely red, hot and swollen joint (often the big toe) with excruciating pain, it’s actually the result of a process that’s been occurring in the body for quite some time. The disease may be chronic for some patients, and for others it may remit for long periods of time, followed by flares for days to weeks.
Continue reading Today is Gout Awareness Day!