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Researchers on the Path to a Cure – Spotlight on Dr. Richard F. Loeser, Jr

Researchers on the Path to a Cure – Spotlight on Dr. Richard F. Loeser, Jr

“You are what you eat” is a phrase we often hear. But how true is it? Dr. Richard F. Loeser, Jr. and his research team are looking at the role of diet in their Arthritis Foundation-funded project “The Role of the Microbiome in Metabolic Osteoarthritis (OA)”. Different factors play into why a person develops OA, including aging, injury, and being overweight. Diet plays an important role. What you eat can help influence what bacteria (or microbiota) live in your digestive track (gut). This, in turn, can influence what chemicals are released into your body. A healthy gut generally has a more ...more
Arthritis Patients Face Increased Risk of Blood Clots

Arthritis Patients Face Increased Risk of Blood Clots

People with autoimmune disease such as lupus and rheumatoid arthritis (RA) are more likely to get dangerous blood clots during hospital stays. In fact, one 2014 Arthritis Research & Therapy meta-analysis of 25 studies found that people with inflammatory rheumatic diseases were three times more likely to experience venous thromboembolisms (VTEs, or blood clots in the veins) than the general population. Lupus patients are four times more likely than people without an autoimmune disease to develop blood clots when hospitalized. And RA patients are one-and-a-half times more likely to develop blood clots during a hospital stay. According to a 2011 study ...more
Going Organic?

Going Organic?

If you’re bypassing organic fruits and vegetables because of their higher prices, you may wonder if you’re shortchanging your health to save money. Even if non-organic produce isn’t doing you any harm, could organic be healthier? In terms of nutrient quality, a scientific review of 162 studies published in 2009 in The American Journal of Clinical Nutrition found no significant differences between organic and conventionally grown produce. On the worrisome side, conventional growing incorporates pesticides, and pesticide exposure has been linked to a range of risks, including cancer, lupus and rheumatoid arthritis. The big caveat: Most of the evidence comes from lab ...more
Top Fibro Treatments

Top Fibro Treatments

If you’ve been diagnosed with mild to moderate fibromyalgia, exercise and other non-drug therapies should be your first line of treatment, according to the European League Against Rheumatism (EULAR), an international group of health professionals in rheumatology. EULAR’s updated fibromyalgia treatment recommendations, published in 2016 in Annals of the Rheumatic Diseases, are similar to the 2007 version, but this time they are based on hard evidence, which was scarce 10 years ago, rather than on expert opinions. For the updated guidelines, researchers reviewed 107 research papers. Assessing outcomes for pain, fatigue, sleep and daily functioning, they ranked their recommendations of various ...more
Indianapolis Closes Out the 33rd Annual National Juvenile Arthritis Conference

Indianapolis Closes Out the 33rd Annual National Juvenile Arthritis Conference

Over the weekend, Indianapolis, Indiana played host to the second location of the two 2017 National Juvenile Arthritis Conferences. The Arthritis Foundation welcomed almost 1,000 kids, teens, young adults and their families to an exciting and spirited weekend of education, networking and fun. For the second year in a row, the Arthritis Foundation hosted two JA Conference locations to serve more kids, families and young adults affected by JA and related childhood rheumatic diseases across the country, while also welcoming back returning veteran families. More than 60 percent of Indianapolis attendees were able to experience the JA Conference for the first ...more
Researchers on the Path to a Cure - Spotlight on Dr. Hongsik Cho

Researchers on the Path to a Cure - Spotlight on Dr. Hongsik Cho

Big things come in small packages, and Dr. Hongsik Cho is very familiar with this phenomenon. When we first introduced Dr. Cho in August 2016, he was beginning work on his 2-year Arthritis Foundation-funded project, “A Novel Method of Detecting and Treating Early PTOA Using Smart Nanosome”.  He and his team are studying two things: a new drug and a new drug delivery system.  The drug, called TPCA-1, works to prevent inflammation caused by post-traumatic osteoarthritis (PTOA).  The drug delivery system uses small packets called nanosomes that contain TPCA-1 and a fluorescent dye that illuminates the nanosomes’ path once injected ...more
Aggressive RA Treatment May Prevent Joint Deformities

Aggressive RA Treatment May Prevent Joint Deformities

Thanks to earlier diagnosis and more effective treatments, joint deformities in people with rheumatoid arthritis (RA) are becoming less frequent and severe. What Causes Joint Deformities in RA? In a joint affected by RA, inflammatory cells of the immune system gather in the lining of the joint (called synovium), forming a fibrous layer of abnormal tissue (called pannus). The pannus releases substances that quicken bone erosion, cartilage destruction and damage to the surrounding ligaments. The involved joints lose their shape and alignment, resulting in deformities. Severe deformities lead to loss of joint function and the need for joint replacement surgery. Risk factors for the development ...more
Heart Diet Good for Gout

Heart Diet Good for Gout

A diet that’s best known for promoting heart health may also help gout management. The Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes fresh fruits and vegetables, whole grains and low-fat dairy products, may lower serum uric acid (SUA) levels. In a study published in Clinical Rheumatology in March 2017,  research findings showed that the diet reduced SUA within 30 days, with a sustained effect at 90 days. In an earlier study reported in Arthritis & Rheumatology in August 2016, researchers reported similar finding in some cases. Gout occurs when excess uric acid builds up in the blood and ...more
The 2017 National Juvenile Arthritis Conference Indianapolis Gets the Green Light Today!

The 2017 National Juvenile Arthritis Conference Indianapolis Gets the Green Light Today!

Today, almost 1,000 kids, teens, young adults and their families from across the country are joining together in the Hoosier state for the second of two national Juvenile Arthritis (JA) Conferences the Arthritis Foundation is hosting this year. The JA Conference is a unique opportunity to connect families, kids, teens and young adults affected by JA and related childhood rheumatic diseases who spend the weekend networking, learning, sharing tips and forming bonds that can last a lifetime. Held at the charming Hyatt Regency in the heart of downtown Indianapolis, a bustling area filled with restaurants and public parks and minutes away from Indianapolis Motor ...more
Researchers on the Path to a Cure – Spotlight on Dr. James Jarvis

Researchers on the Path to a Cure – Spotlight on Dr. James Jarvis

“Why did my child get arthritis?” This parent-driven question is at the heart of Dr. Jim Jarvis’s juvenile idiopathic arthritis (JIA) Arthritis Foundation-funded project, “Interplay between genetics and epigenetics in polyarticular JIA”. “This is less about an illness driven by inherited genes and more about how the environment affects gene expression,” explained Dr. Jarvis. “It’s been shown that only about 30 percent of the risk for developing JIA can be attributed to gene variations.” Epigenetics looks at the ways that genes and the environment interact and effect DNA and DNA expression.  This project is based on the idea that JIA develops because ...more