Like most people with arthritis, you probably have symptoms that are better at some times of day than others. Rheumatoid arthritis (RA) is usually worse in the morning, for instance, whereas gout more frequently flares in the evening, and pain from fibromyalgia (like other conditions) is more intense after a poor night’s sleep. Researchers believe these variations in the timing and severity of arthritis symptoms may result from disruptions in circadian rhythms – the 24-hour cycles of biologic activity that regulate sleep, immune response and many other functions.
Cortisol: At the Heart of the Matter
Maurizio Cutolo, MD, a professor of rheumatology ...more